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This is a rush transcript of “Special Report With Brit Hume” from November 20, 2008. This copy may not be in its final form and may be updated. (BEGIN VIDEO CLIP) PATRICK LEAHY, (D-VT) SENATE JUDICIARY COMMITTEE: I have known Eric Holder for a year. If he is President-elect Obama’s …

If breast cancer runs in the family, women can be at high risk even if they test free of the disease’s most common gene mutations, sobering new research shows. The genes BRCA1 and BRCA2 are linked with particularly aggressive hereditary breast cancer, and an increased risk of ovarian cancer, too. …

EAST BANK, W.Va. – A Kanawha County police officer has been fired after he admitted using a Taser on a pregnant teenager and a firefighter. East Bank Mayor Chuck Blair says Sgt. Steve Smith was fired after the Town Council learned of the incidents in September. Smith had been on …